Endocrine Abstracts

Introduction: Although the syndrome of inappropriate antidiuretic hormone (SIADH) has connection with various malignant tumors, the pituitary metastasis of malignant tumors are generally associated with diabetes insipidus.Case report: A 59 years old male patient presented to emergency service with frequent syncope attacks, nausea, loss of appetite and fatigue that began 2 weeks prior to admission. Marked obtundation was found on physical examination. The...

Introduction: The results of publications investigating the relationship between low maternal serum 25-hydroxyvitamin D (25OHD) level and gestational diabetes mellitus (GDM) are controversial and none of these publications have investigated this relationship according to the severity of 25OHD deficiency. Therefore, this study was conducted to assess the relationship between low maternal serum 25OHD and GDM according to the severity of 25OHD deficiency.Me...

Objective: It is not currently well known whether pheochromocytomas can be ruled out based on low intensity on T2-weighted sequences and signal loss on out-off phase magnetic resonance imaging (MRI) sequences. Hence, in this study we aimed to investigate whether biochemical screening for pheochromocytoma in patients with adrenal incidentalomas (AI) showing MRI features not suggesting pheochromocytoma would prove beneficial.Methods: We performed MRI for 3...

Introduction and aim: Osteopetrosis is a rare genetic disorder of reduced osteoclastic bone resorption. Defective bone remodelling induces skeletal sclerosis and abnormally dense but brittle bones. We present here a case of autosomal dominant osteopetrosis type II as a cause of high bone mineral density (BMD).Case report: A 52-years-old woman with a complaint of bone pain and headache referred to our clinic for evaluation of high BMD. Her medical history...

Introduction: Thyrotropin secreting pituitary adenomas are rare constituting <2% of pituitary adenomas. Thirty percent of these tumors may be plurihormonal. Most common cosecreted hormone is GH and the least one is PRL. We report here a case of plurihormonal pituitary adenoma symptomatic for TSH secretion.Case report: A 35-year-old female admitted to hospital because of fatigue, heat intolerance, headache, galactorrhea and menstrual irregularity. Her...

Thyroidectomy is the definitive treatment for toxic multinodular goiter (TXMNG). Surgery should be performed when the patient is euthyroid which decreases perioperative cardiac risks. Plasmapheresis is a procedure that removes the thyroid hormones from the circulation. It is an alternative method in case of resistance or contraindications to anti thyroid drugs. Role of plasmapheresis in the treatment of TXMNG is not fully determined in the literature. We report a case with TXM...

Introduction: Sertoli–Leydig cell tumours are rare tumours which account for <1% of all solid ovarian tumors. It mostly occurs in 2–4° decades of life. Rapidly progessing symptoms/signs of androgen excess suggest the presence of and androgen secreting tumor.Case: Two postmenopausal patients (50 and 57 year-old) were referred to our Endocrinology Clinic for evaluation of worsening hirsutism. Both of patients had manifestations of hypera...

Objective: To compare the roles of inferior thyroid artery (ITA) peak systolic and end-diastolic velocities (PSV and EDV) measured by color flow Doppler ultrasonography (CFDUSG), TSH receptor antibody (TRAb) measured by M22 based ELISA and Tc-99m pertechnetate uptake for differential diagnosis between Graves’ disease (GD) and silent thyroiditis (ST).Methods: One hundred and fifty previously untreated subjects with GD (111 female, 39 male, mean age 3...

Introduction: APECED syndrome is characterized by the three most common components of the condition, i.e. mucocutaneous candidiasis, autoimmune hypoparathyroidism, and Addison’s disease. Presence of two of these components suffices for diagnosis.The case: A 33-year-old female patient presented to the endocrinology polyclinic for weakness, nausea, vomiting, dizziness, recurring vaginal itch, and discharge for 1 year, intermittent dysphagias and ameno...